Side-by-Side Comparison · 2026

Adamax vs Cortexin

Adamax vs Cortexin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Adamax
Cognitive & Neurological

Adamax is a branded formulation of N-Acetyl Semax Amidate, the most potent and longest-acting analog of the nootropic peptide Semax. The N-acetyl modification at the N-terminus and amide modification at the C-terminus together extend its half-life and increase BDNF-stimulating po...

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Cortexin
Cognitive & Neurological

Cortexin is a polypeptide complex extracted from the cerebral cortex of pigs (porcine origin) that contains a mixture of low-molecular-weight neuropeptides, amino acids, and protein fractions. It is an approved drug in Russia, used clinically for stroke recovery, traumatic brain ...

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Key Parameters
Parameter Adamax Cortexin
Category Cognitive & Neurological Cognitive & Neurological
Research Research Use Approved (Russia/CIS)
Half-Life ~8–12 hours (extended vs. standard Semax) -
Typical Dose 100–300 µg 10 mg
Frequency Once or twice daily Once daily
Route Intranasal Intramuscular
FDA Status Not Approved Not Approved

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Frequently Asked Questions
What is the difference between Adamax and Cortexin?
Adamax: Adamax is a branded formulation of N-Acetyl Semax Amidate, the most potent and longest-acting analog of the nootropic peptide Semax. The N-acetyl modification at the N-terminus and amide modification ... Cortexin: Cortexin is a polypeptide complex extracted from the cerebral cortex of pigs (porcine origin) that contains a mixture of low-molecular-weight neuropeptides, amino acids, and protein fractions. It is a...
Which has a longer half-life, Adamax or Cortexin?
Adamax half-life: ~8–12 hours (extended vs. standard Semax). Cortexin half-life: unknown.
Can you stack Adamax and Cortexin?
Adamax and Cortexin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.