Side-by-Side Comparison · 2026

Adrenomedullin vs Relaxin-2

Adrenomedullin vs Relaxin-2 — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Adrenomedullin
Cardiovascular Peptide

Adrenomedullin (ADM) is a 52-amino acid vasoactive peptide first isolated from human pheochromocytoma tissue in 1993. It is now recognized as a pleiotropic hormone produced widely throughout the body, with highest expression in the adrenal medulla, heart, lung, kidney, and vascul...

Calculate Adrenomedullin dose →
Relaxin-2
Cardiovascular Peptide

Relaxin-2 (H2 Relaxin) is an endogenous peptide hormone of the insulin superfamily, best known for its roles in pregnancy physiology including cervical ripening, uterine quiescence, and connective tissue remodeling. Beyond reproduction, relaxin-2 is a systemic anti-fibrotic and v...

Calculate Relaxin-2 dose →
Key Parameters
Parameter Adrenomedullin Relaxin-2
Category Cardiovascular Peptide Cardiovascular Peptide
Research Clinical Clinical
Half-Life 22 min (plasma) 10-15 min (plasma)
Typical Dose 2-10 ng/kg/min (IV infusion) 30-300 mcg/kg/day (IV)
Frequency Acute infusion or short course Continuous 48-hour infusion (trials)
Route Intravenous, Subcutaneous Intravenous (infusion)
FDA Status Not approved Not approved (Phase III completed)

Calculate doses for both

Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.

Calculate Adrenomedullin Calculate Relaxin-2
Frequently Asked Questions
What is the difference between Adrenomedullin and Relaxin-2?
Adrenomedullin: Adrenomedullin (ADM) is a 52-amino acid vasoactive peptide first isolated from human pheochromocytoma tissue in 1993. It is now recognized as a pleiotropic hormone produced widely throughout the body,... Relaxin-2: Relaxin-2 (H2 Relaxin) is an endogenous peptide hormone of the insulin superfamily, best known for its roles in pregnancy physiology including cervical ripening, uterine quiescence, and connective tis...
Which has a longer half-life, Adrenomedullin or Relaxin-2?
Adrenomedullin half-life: 22 min (plasma). Relaxin-2 half-life: 10-15 min (plasma).
Can you stack Adrenomedullin and Relaxin-2?
Adrenomedullin and Relaxin-2 are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.