Side-by-Side Comparison · 2026

Adrenomedullin vs Vasostatin

Adrenomedullin vs Vasostatin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Adrenomedullin
Cardiovascular Peptide

Adrenomedullin (ADM) is a 52-amino acid vasoactive peptide first isolated from human pheochromocytoma tissue in 1993. It is now recognized as a pleiotropic hormone produced widely throughout the body, with highest expression in the adrenal medulla, heart, lung, kidney, and vascul...

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Vasostatin
Cardiovascular Peptide

Vasostatin refers to the N-terminal fragments of chromogranin A (CgA), particularly CgA1-76 (Vasostatin-1) and CgA1-113 (Vasostatin-2), generated by proteolytic processing of the chromogranin A precursor. While catestatin (CgA352-372) is the C-terminal CgA fragment with anti-cate...

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Key Parameters
Parameter Adrenomedullin Vasostatin
Category Cardiovascular Peptide Cardiovascular Peptide
Research Clinical Preclinical Research
Half-Life 22 min (plasma) ~20-30 minutes (estimated)
Typical Dose 2-10 ng/kg/min (IV infusion) 0.1-10 nmol/kg IV (animal)
Frequency Acute infusion or short course Acute dosing
Route Intravenous, Subcutaneous IV (research)
FDA Status Not approved Research compound

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Frequently Asked Questions
What is the difference between Adrenomedullin and Vasostatin?
Adrenomedullin: Adrenomedullin (ADM) is a 52-amino acid vasoactive peptide first isolated from human pheochromocytoma tissue in 1993. It is now recognized as a pleiotropic hormone produced widely throughout the body,... Vasostatin: Vasostatin refers to the N-terminal fragments of chromogranin A (CgA), particularly CgA1-76 (Vasostatin-1) and CgA1-113 (Vasostatin-2), generated by proteolytic processing of the chromogranin A precur...
Which has a longer half-life, Adrenomedullin or Vasostatin?
Adrenomedullin half-life: 22 min (plasma). Vasostatin half-life: ~20-30 minutes (estimated).
Can you stack Adrenomedullin and Vasostatin?
Adrenomedullin and Vasostatin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.