Side-by-Side Comparison · 2026

Adropin vs Asprosin

Adropin vs Asprosin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Adropin
Metabolic Peptide

Adropin is a secreted peptide encoded by the Energy Homeostasis-Associated (ENHO) gene, expressed predominantly in the liver and brain. The mature circulating form (adropin 34-76) is a 43-amino acid peptide detected in plasma and CSF....

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Asprosin
Metabolic Peptide

Asprosin is a 30 kDa protein hormone discovered in 2016 as the C-terminal cleavage product of fibrillin-1, encoded by the FBN1 gene. It is secreted by white adipose tissue in response to fasting and acts on the hypothalamus and liver....

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Key Parameters
Parameter Adropin Asprosin
Category Metabolic Peptide Metabolic Peptide
Research Preclinical / Early Human Preclinical / Early Clinical
Half-Life ~10-20 minutes (estimated) ~30-60 minutes
Typical Dose 0.1-1 nmol/kg (animal studies) 10-100 ng/mL plasma concentration range (physiological)
Frequency Single or twice daily (preclinical) N/A (endogenous hormone)
Route IV/IP (preclinical); endogenous IV (research); endogenous
FDA Status Research compound Research compound; anti-asprosin antibodies in development

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Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.

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Frequently Asked Questions
What is the difference between Adropin and Asprosin?
Adropin: Adropin is a secreted peptide encoded by the Energy Homeostasis-Associated (ENHO) gene, expressed predominantly in the liver and brain. The mature circulating form (adropin 34-76) is a 43-amino acid p... Asprosin: Asprosin is a 30 kDa protein hormone discovered in 2016 as the C-terminal cleavage product of fibrillin-1, encoded by the FBN1 gene. It is secreted by white adipose tissue in response to fasting and a...
Which has a longer half-life, Adropin or Asprosin?
Adropin half-life: ~10-20 minutes (estimated). Asprosin half-life: ~30-60 minutes.
Can you stack Adropin and Asprosin?
Adropin and Asprosin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.