Side-by-Side Comparison · 2026

AHK-Cu vs GHK

AHK-Cu vs GHK — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

AHK-Cu
Skin & Cosmetic

AHK-Cu is a copper-chelating tripeptide (Ala-His-Lys) that functions as a hair follicle stimulant and skin regeneration signal. Related to the more widely studied GHK-Cu, AHK-Cu has shown specific activity in promoting hair follicle stem cell proliferation and inhibiting DHT-rela...

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GHK
Skin & Cosmetic

GHK (Glycyl-L-Histidyl-L-Lysine) is the copper-free form of the GHK-Cu tripeptide. While GHK-Cu (GHK chelated to copper) is more widely studied for wound healing and tissue repair, GHK alone retains some bioactivity, particularly for signaling collagen synthesis and gene expressi...

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Key Parameters
Parameter AHK-Cu GHK
Category Skin & Cosmetic Skin & Cosmetic
Research Research Use Research Use
Half-Life - -
Typical Dose 2–5% solution 1–5% topical; 1–2 mg/mL injectable
Frequency Once or twice daily Once or twice daily
Route Topical Topical / Injectable
FDA Status Not Approved (Cosmetic) Not Approved (Cosmetic)

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Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.

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Frequently Asked Questions
What is the difference between AHK-Cu and GHK?
AHK-Cu: AHK-Cu is a copper-chelating tripeptide (Ala-His-Lys) that functions as a hair follicle stimulant and skin regeneration signal. Related to the more widely studied GHK-Cu, AHK-Cu has shown specific act... GHK: GHK (Glycyl-L-Histidyl-L-Lysine) is the copper-free form of the GHK-Cu tripeptide. While GHK-Cu (GHK chelated to copper) is more widely studied for wound healing and tissue repair, GHK alone retains s...
Which has a longer half-life, AHK-Cu or GHK?
AHK-Cu half-life: unknown. GHK half-life: unknown.
Can you stack AHK-Cu and GHK?
AHK-Cu and GHK are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.