Side-by-Side Comparison · 2026

Angiotensin 1-9 vs Intermedin

Angiotensin 1-9 vs Intermedin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Angiotensin 1-9
Cardiovascular Peptide

Angiotensin 1-9 (Ang 1-9) is a 9-amino acid peptide formed when ACE2 cleaves the C-terminal leucine from angiotensin I (Ang I, 10 AA). Discovered as part of the counter-regulatory renin-angiotensin system (RAS), Ang 1-9 opposes the hypertensive and tissue-damaging actions of angi...

Calculate Angiotensin 1-9 dose →
Intermedin
Cardiovascular Peptide

Intermedin (also called Adrenomedullin 2, AM2) is a 47-53 amino acid peptide belonging to the calcitonin gene-related peptide (CGRP)/adrenomedullin superfamily. Discovered in 2004, intermedin is widely expressed in the heart, lung, kidney, gut, and brain....

Calculate Intermedin dose →
Key Parameters
Parameter Angiotensin 1-9 Intermedin
Category Cardiovascular Peptide Cardiovascular Peptide
Research Preclinical Research Preclinical Research
Half-Life ~20-30 minutes ~15-30 minutes
Typical Dose 40-400 ng/kg/min IV infusion (animal) 1-100 pmol/kg/min infusion (animal)
Frequency Acute infusion protocols Acute infusion
Route IV/SC (research) IV (research); SC in some studies
FDA Status Research compound Research compound

Calculate doses for both

Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.

Calculate Angiotensin 1-9 Calculate Intermedin
Frequently Asked Questions
What is the difference between Angiotensin 1-9 and Intermedin?
Angiotensin 1-9: Angiotensin 1-9 (Ang 1-9) is a 9-amino acid peptide formed when ACE2 cleaves the C-terminal leucine from angiotensin I (Ang I, 10 AA). Discovered as part of the counter-regulatory renin-angiotensin sy... Intermedin: Intermedin (also called Adrenomedullin 2, AM2) is a 47-53 amino acid peptide belonging to the calcitonin gene-related peptide (CGRP)/adrenomedullin superfamily. Discovered in 2004, intermedin is widel...
Which has a longer half-life, Angiotensin 1-9 or Intermedin?
Angiotensin 1-9 half-life: ~20-30 minutes. Intermedin half-life: ~15-30 minutes.
Can you stack Angiotensin 1-9 and Intermedin?
Angiotensin 1-9 and Intermedin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.