Side-by-Side Comparison · 2026

Apelin-17 vs Catestatin

Apelin-17 vs Catestatin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Apelin-17
Cardiovascular Peptide

Apelin-17 is a 17-amino acid C-terminal fragment of the prepro-apelin precursor that binds and activates the APJ receptor (now APLNR) with the highest potency of all naturally occurring apelin isoforms. While apelin-13 is the best-characterized isoform, apelin-17 shows greater re...

Calculate Apelin-17 dose →
Catestatin
Cardiovascular Peptide

Catestatin is a 21-amino acid peptide derived from the chromogranin A (CgA) protein, specifically cleaved from the region spanning residues 352-372. It was identified as an endogenous inhibitor of catecholamine secretion, acting as a non-competitive antagonist at nicotinic acetyl...

Calculate Catestatin dose →
Key Parameters
Parameter Apelin-17 Catestatin
Category Cardiovascular Peptide Cardiovascular Peptide
Research Preclinical / Phase I Preclinical / Early Human
Half-Life ~3-5 minutes IV (longer than apelin-13) ~15-30 minutes (IV)
Typical Dose 30-100 nmol/kg/min (IV infusion, clinical) 0.3-3 nmol/kg (animal studies)
Frequency Acute infusion protocols Acute dosing in research
Route IV infusion (clinical studies); SC under investigation IV (research); intranasal under study
FDA Status Investigational (Phase I/II) Research compound

Calculate doses for both

Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.

Calculate Apelin-17 Calculate Catestatin
Frequently Asked Questions
What is the difference between Apelin-17 and Catestatin?
Apelin-17: Apelin-17 is a 17-amino acid C-terminal fragment of the prepro-apelin precursor that binds and activates the APJ receptor (now APLNR) with the highest potency of all naturally occurring apelin isoform... Catestatin: Catestatin is a 21-amino acid peptide derived from the chromogranin A (CgA) protein, specifically cleaved from the region spanning residues 352-372. It was identified as an endogenous inhibitor of cat...
Which has a longer half-life, Apelin-17 or Catestatin?
Apelin-17 half-life: ~3-5 minutes IV (longer than apelin-13). Catestatin half-life: ~15-30 minutes (IV).
Can you stack Apelin-17 and Catestatin?
Apelin-17 and Catestatin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.