Side-by-Side Comparison · 2026

Arenicin vs Omiganan

Arenicin vs Omiganan — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Arenicin
Antimicrobial Peptide

Arenicin is a beta-hairpin antimicrobial peptide isolated from the coelomocytes of the lugworm Arenicola marina. It features a cyclic disulfide-bridged structure that confers broad-spectrum antibacterial and antifungal activity....

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Omiganan
Antimicrobial Peptide

Omiganan (CLS001, MBI-226) is a synthetic analog of indolicidin, a bovine neutrophil AMP. It was developed for topical antimicrobial applications including acne vulgaris, catheter-site infection prevention, and rosacea....

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Key Parameters
Parameter Arenicin Omiganan
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Phase 3 (Completed)
Half-Life Short (minutes in plasma) Hours (topical)
Typical Dose N/A (research only) 1-3% gel
Frequency N/A Twice daily
Route Topical / Systemic (research) Topical gel/cream
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between Arenicin and Omiganan?
Arenicin: Arenicin is a beta-hairpin antimicrobial peptide isolated from the coelomocytes of the lugworm Arenicola marina. It features a cyclic disulfide-bridged structure that confers broad-spectrum antibacter... Omiganan: Omiganan (CLS001, MBI-226) is a synthetic analog of indolicidin, a bovine neutrophil AMP. It was developed for topical antimicrobial applications including acne vulgaris, catheter-site infection preve...
Which has a longer half-life, Arenicin or Omiganan?
Arenicin half-life: Short (minutes in plasma). Omiganan half-life: Hours (topical).
Can you stack Arenicin and Omiganan?
Arenicin and Omiganan are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.