Side-by-Side Comparison · 2026

Arenicin vs Plectasin

Arenicin vs Plectasin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Arenicin
Antimicrobial Peptide

Arenicin is a beta-hairpin antimicrobial peptide isolated from the coelomocytes of the lugworm Arenicola marina. It features a cyclic disulfide-bridged structure that confers broad-spectrum antibacterial and antifungal activity....

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Plectasin
Antimicrobial Peptide

Plectasin is a 40-residue defensin-like antimicrobial peptide discovered in 2005 from the saprophytic fungus Pseudoplectania nigrella. It was the first AMP isolated from a fungal organism....

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Key Parameters
Parameter Arenicin Plectasin
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Preclinical
Half-Life Short (minutes in plasma) Hours (disulfide stabilized)
Typical Dose N/A (research only) N/A
Frequency N/A N/A
Route Topical / Systemic (research) Research only
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between Arenicin and Plectasin?
Arenicin: Arenicin is a beta-hairpin antimicrobial peptide isolated from the coelomocytes of the lugworm Arenicola marina. It features a cyclic disulfide-bridged structure that confers broad-spectrum antibacter... Plectasin: Plectasin is a 40-residue defensin-like antimicrobial peptide discovered in 2005 from the saprophytic fungus Pseudoplectania nigrella. It was the first AMP isolated from a fungal organism....
Which has a longer half-life, Arenicin or Plectasin?
Arenicin half-life: Short (minutes in plasma). Plectasin half-life: Hours (disulfide stabilized).
Can you stack Arenicin and Plectasin?
Arenicin and Plectasin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.