Side-by-Side Comparison · 2026

Aurein vs Cathelicidin (LL-37)

Aurein vs Cathelicidin (LL-37) — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Aurein
Antimicrobial Peptide

Aurein peptides are a large family of short (13-25 residue) antimicrobial and anticancer peptides isolated from the Australian green and golden bell frog Litoria aurea and related species. 2 is the smallest member with activity against Gram-positive bacteria....

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Cathelicidin (LL-37)
Antimicrobial Peptide

LL-37 is the sole human cathelicidin antimicrobial peptide, derived by proteolytic cleavage of the 18 kDa precursor hCAP18 (encoded by the CAMP gene). It is produced by neutrophils, epithelial cells of the skin, gut, and airways, and mast cells....

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Key Parameters
Parameter Aurein Cathelicidin (LL-37)
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Clinical Research
Half-Life Minutes (proteolytic) < 10 min (plasma)
Typical Dose N/A Research: 1-100 ug/mL (topical)
Frequency N/A Varies by application
Route Research only Endogenous; topical/inhalation (research)
FDA Status Not approved No approval (clinical trials ongoing)

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Frequently Asked Questions
What is the difference between Aurein and Cathelicidin (LL-37)?
Aurein: Aurein peptides are a large family of short (13-25 residue) antimicrobial and anticancer peptides isolated from the Australian green and golden bell frog Litoria aurea and related species. 2 is the sm... Cathelicidin (LL-37): LL-37 is the sole human cathelicidin antimicrobial peptide, derived by proteolytic cleavage of the 18 kDa precursor hCAP18 (encoded by the CAMP gene). It is produced by neutrophils, epithelial cells o...
Which has a longer half-life, Aurein or Cathelicidin (LL-37)?
Aurein half-life: Minutes (proteolytic). Cathelicidin (LL-37) half-life: < 10 min (plasma).
Can you stack Aurein and Cathelicidin (LL-37)?
Aurein and Cathelicidin (LL-37) are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.