Side-by-Side Comparison · 2026

Aurein vs PR-39

Aurein vs PR-39 — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Aurein
Antimicrobial Peptide

Aurein peptides are a large family of short (13-25 residue) antimicrobial and anticancer peptides isolated from the Australian green and golden bell frog Litoria aurea and related species. 2 is the smallest member with activity against Gram-positive bacteria....

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PR-39
Antimicrobial Peptide

PR-39 is a 39-residue proline- and arginine-rich antimicrobial peptide from porcine neutrophil granules. Unlike classical membrane-disrupting AMPs, PR-39 kills bacteria intracellularly by inhibiting DNA and protein synthesis....

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Key Parameters
Parameter Aurein PR-39
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Preclinical
Half-Life Minutes (proteolytic) Minutes (proteolytic)
Typical Dose N/A N/A
Frequency N/A N/A
Route Research only Research only
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between Aurein and PR-39?
Aurein: Aurein peptides are a large family of short (13-25 residue) antimicrobial and anticancer peptides isolated from the Australian green and golden bell frog Litoria aurea and related species. 2 is the sm... PR-39: PR-39 is a 39-residue proline- and arginine-rich antimicrobial peptide from porcine neutrophil granules. Unlike classical membrane-disrupting AMPs, PR-39 kills bacteria intracellularly by inhibiting D...
Which has a longer half-life, Aurein or PR-39?
Aurein half-life: Minutes (proteolytic). PR-39 half-life: Minutes (proteolytic).
Can you stack Aurein and PR-39?
Aurein and PR-39 are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.