Side-by-Side Comparison · 2026

CART Peptide vs Relaxin-3

CART Peptide vs Relaxin-3 — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

CART Peptide
Neuropeptide

CART (Cocaine- and Amphetamine-Regulated Transcript) peptide is a neuropeptide encoded by the CARTPT gene, named because its mRNA is dramatically upregulated in the striatum by cocaine and amphetamine administration. CART peptide is produced in the arcuate nucleus, nucleus accumb...

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Relaxin-3
Neuropeptide

Relaxin-3 (also called INSL7) is the most ancient member of the insulin/relaxin superfamily and is expressed predominantly in the nucleus incertus (NI) of the brainstem, a structure implicated in stress, arousal, and hippocampal theta rhythm generation. Unlike relaxin-1 and relax...

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Key Parameters
Parameter CART Peptide Relaxin-3
Category Neuropeptide Neuropeptide
Research Research Preclinical Research
Half-Life Unknown ~30-60 minutes (estimated)
Typical Dose 0.1-10 nmol (ICV, animal) 100-500 pmol ICV; 1-3 nmol/kg SC
Frequency Variable Single or twice daily (preclinical)
Route Intracerebroventricular (animal research) ICV, SC (preclinical)
FDA Status Not approved Research compound

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Frequently Asked Questions
What is the difference between CART Peptide and Relaxin-3?
CART Peptide: CART (Cocaine- and Amphetamine-Regulated Transcript) peptide is a neuropeptide encoded by the CARTPT gene, named because its mRNA is dramatically upregulated in the striatum by cocaine and amphetamine... Relaxin-3: Relaxin-3 (also called INSL7) is the most ancient member of the insulin/relaxin superfamily and is expressed predominantly in the nucleus incertus (NI) of the brainstem, a structure implicated in stre...
Which has a longer half-life, CART Peptide or Relaxin-3?
CART Peptide half-life: Unknown. Relaxin-3 half-life: ~30-60 minutes (estimated).
Can you stack CART Peptide and Relaxin-3?
CART Peptide and Relaxin-3 are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.