Side-by-Side Comparison · 2026

Catestatin vs Elabela

Catestatin vs Elabela — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Catestatin
Cardiovascular Peptide

Catestatin is a 21-amino acid peptide derived from the chromogranin A (CgA) protein, specifically cleaved from the region spanning residues 352-372. It was identified as an endogenous inhibitor of catecholamine secretion, acting as a non-competitive antagonist at nicotinic acetyl...

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Elabela
Cardiovascular Peptide

Elabela (also called Apela or Toddler) is the second endogenous peptide ligand for the APJ receptor, discovered in 2013 independently through two approaches: as an essential zebrafish cardiac development factor (Toddler) and as a novel human APJ ligand (Elabela). Unlike apelin pe...

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Key Parameters
Parameter Catestatin Elabela
Category Cardiovascular Peptide Cardiovascular Peptide
Research Preclinical / Early Human Research
Half-Life ~15-30 minutes (IV) Short (minutes, estimated)
Typical Dose 0.3-3 nmol/kg (animal studies) 5-500 nmol/kg (animal)
Frequency Acute dosing in research Variable
Route IV (research); intranasal under study Subcutaneous, Intravenous
FDA Status Research compound Not approved

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Frequently Asked Questions
What is the difference between Catestatin and Elabela?
Catestatin: Catestatin is a 21-amino acid peptide derived from the chromogranin A (CgA) protein, specifically cleaved from the region spanning residues 352-372. It was identified as an endogenous inhibitor of cat... Elabela: Elabela (also called Apela or Toddler) is the second endogenous peptide ligand for the APJ receptor, discovered in 2013 independently through two approaches: as an essential zebrafish cardiac developm...
Which has a longer half-life, Catestatin or Elabela?
Catestatin half-life: ~15-30 minutes (IV). Elabela half-life: Short (minutes, estimated).
Can you stack Catestatin and Elabela?
Catestatin and Elabela are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.