Side-by-Side Comparison · 2026

Catestatin vs Intermedin

Catestatin vs Intermedin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Catestatin
Cardiovascular Peptide

Catestatin is a 21-amino acid peptide derived from the chromogranin A (CgA) protein, specifically cleaved from the region spanning residues 352-372. It was identified as an endogenous inhibitor of catecholamine secretion, acting as a non-competitive antagonist at nicotinic acetyl...

Calculate Catestatin dose →
Intermedin
Cardiovascular Peptide

Intermedin (also called Adrenomedullin 2, AM2) is a 47-53 amino acid peptide belonging to the calcitonin gene-related peptide (CGRP)/adrenomedullin superfamily. Discovered in 2004, intermedin is widely expressed in the heart, lung, kidney, gut, and brain....

Calculate Intermedin dose →
Key Parameters
Parameter Catestatin Intermedin
Category Cardiovascular Peptide Cardiovascular Peptide
Research Preclinical / Early Human Preclinical Research
Half-Life ~15-30 minutes (IV) ~15-30 minutes
Typical Dose 0.3-3 nmol/kg (animal studies) 1-100 pmol/kg/min infusion (animal)
Frequency Acute dosing in research Acute infusion
Route IV (research); intranasal under study IV (research); SC in some studies
FDA Status Research compound Research compound

Calculate doses for both

Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.

Calculate Catestatin Calculate Intermedin
Frequently Asked Questions
What is the difference between Catestatin and Intermedin?
Catestatin: Catestatin is a 21-amino acid peptide derived from the chromogranin A (CgA) protein, specifically cleaved from the region spanning residues 352-372. It was identified as an endogenous inhibitor of cat... Intermedin: Intermedin (also called Adrenomedullin 2, AM2) is a 47-53 amino acid peptide belonging to the calcitonin gene-related peptide (CGRP)/adrenomedullin superfamily. Discovered in 2004, intermedin is widel...
Which has a longer half-life, Catestatin or Intermedin?
Catestatin half-life: ~15-30 minutes (IV). Intermedin half-life: ~15-30 minutes.
Can you stack Catestatin and Intermedin?
Catestatin and Intermedin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.