Side-by-Side Comparison · 2026

Cathelicidin (LL-37) vs Indolicidin

Cathelicidin (LL-37) vs Indolicidin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Cathelicidin (LL-37)
Antimicrobial Peptide

LL-37 is the sole human cathelicidin antimicrobial peptide, derived by proteolytic cleavage of the 18 kDa precursor hCAP18 (encoded by the CAMP gene). It is produced by neutrophils, epithelial cells of the skin, gut, and airways, and mast cells....

Calculate Cathelicidin (LL-37) dose →
Indolicidin
Antimicrobial Peptide

Indolicidin is a 13-residue, tryptophan-rich antimicrobial peptide from bovine neutrophil granules. It is the smallest naturally occurring AMP with broad-spectrum activity....

Calculate Indolicidin dose →
Key Parameters
Parameter Cathelicidin (LL-37) Indolicidin
Category Antimicrobial Peptide Antimicrobial Peptide
Research Clinical Research Phase II (completed)
Half-Life < 10 min (plasma) Minutes to hours
Typical Dose Research: 1-100 ug/mL (topical) N/A
Frequency Varies by application N/A
Route Endogenous; topical/inhalation (research) Topical
FDA Status No approval (clinical trials ongoing) Not approved

Calculate doses for both

Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.

Calculate Cathelicidin (LL-37) Calculate Indolicidin
Frequently Asked Questions
What is the difference between Cathelicidin (LL-37) and Indolicidin?
Cathelicidin (LL-37): LL-37 is the sole human cathelicidin antimicrobial peptide, derived by proteolytic cleavage of the 18 kDa precursor hCAP18 (encoded by the CAMP gene). It is produced by neutrophils, epithelial cells o... Indolicidin: Indolicidin is a 13-residue, tryptophan-rich antimicrobial peptide from bovine neutrophil granules. It is the smallest naturally occurring AMP with broad-spectrum activity....
Which has a longer half-life, Cathelicidin (LL-37) or Indolicidin?
Cathelicidin (LL-37) half-life: < 10 min (plasma). Indolicidin half-life: Minutes to hours.
Can you stack Cathelicidin (LL-37) and Indolicidin?
Cathelicidin (LL-37) and Indolicidin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.