Side-by-Side Comparison · 2026

Cecropin vs Plectasin

Cecropin vs Plectasin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Cecropin
Antimicrobial Peptide

Cecropins are a family of antimicrobial peptides first discovered in 1980 by Hans Boman in the silkmoth Hyalophora cecropia. Cecropin A was the first AMP characterized from an insect, establishing the paradigm of innate immune peptide-based defense....

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Plectasin
Antimicrobial Peptide

Plectasin is a 40-residue defensin-like antimicrobial peptide discovered in 2005 from the saprophytic fungus Pseudoplectania nigrella. It was the first AMP isolated from a fungal organism....

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Key Parameters
Parameter Cecropin Plectasin
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Preclinical
Half-Life Minutes (proteolytic) Hours (disulfide stabilized)
Typical Dose N/A N/A
Frequency N/A N/A
Route Research only Research only
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between Cecropin and Plectasin?
Cecropin: Cecropins are a family of antimicrobial peptides first discovered in 1980 by Hans Boman in the silkmoth Hyalophora cecropia. Cecropin A was the first AMP characterized from an insect, establishing the... Plectasin: Plectasin is a 40-residue defensin-like antimicrobial peptide discovered in 2005 from the saprophytic fungus Pseudoplectania nigrella. It was the first AMP isolated from a fungal organism....
Which has a longer half-life, Cecropin or Plectasin?
Cecropin half-life: Minutes (proteolytic). Plectasin half-life: Hours (disulfide stabilized).
Can you stack Cecropin and Plectasin?
Cecropin and Plectasin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.