Side-by-Side Comparison · 2026

CJC-1295 No-DAC vs CJC-1295 with DAC

CJC-1295 No-DAC vs CJC-1295 with DAC — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

CJC-1295 No-DAC
Growth Hormone & IGF

CJC-1295 No-DAC (also called Modified GRF 1-29 or Mod GRF) is a short-acting GHRH (Growth Hormone-Releasing Hormone) analog consisting of the first 29 amino acids of endogenous GHRH with four amino acid substitutions to improve stability and receptor binding....

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CJC-1295 with DAC
Growth Hormone & IGF

CJC-1295 with DAC is a long-acting GHRH analog that uses a Drug Affinity Complex (DAC) technology - a reactive maleimidoproprionic acid linker that covalently bonds to plasma albumin after injection. This albumin binding dramatically extends its half-life to 6-8 days, allowing on...

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Key Parameters
Parameter CJC-1295 No-DAC CJC-1295 with DAC
Category Growth Hormone & IGF Growth Hormone & IGF
Research Research Use Research Use
Half-Life 30 minutes 6–8 days
Typical Dose 100–200 µg 1,000–2,000 µg
Frequency 2–3x daily Once or twice weekly
Route Subcutaneous Subcutaneous
FDA Status Not Approved Not Approved

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Frequently Asked Questions
What is the difference between CJC-1295 No-DAC and CJC-1295 with DAC?
CJC-1295 No-DAC: CJC-1295 No-DAC (also called Modified GRF 1-29 or Mod GRF) is a short-acting GHRH (Growth Hormone-Releasing Hormone) analog consisting of the first 29 amino acids of endogenous GHRH with four amino ac... CJC-1295 with DAC: CJC-1295 with DAC is a long-acting GHRH analog that uses a Drug Affinity Complex (DAC) technology - a reactive maleimidoproprionic acid linker that covalently bonds to plasma albumin after injection. ...
Which has a longer half-life, CJC-1295 No-DAC or CJC-1295 with DAC?
CJC-1295 No-DAC half-life: 30 minutes. CJC-1295 with DAC half-life: 6–8 days.
Can you stack CJC-1295 No-DAC and CJC-1295 with DAC?
CJC-1295 No-DAC and CJC-1295 with DAC are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.