Side-by-Side Comparison · 2026

CJC-1295 No-DAC vs MK-677

CJC-1295 No-DAC vs MK-677 — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

CJC-1295 No-DAC
Growth Hormone & IGF

CJC-1295 No-DAC (also called Modified GRF 1-29 or Mod GRF) is a short-acting GHRH (Growth Hormone-Releasing Hormone) analog consisting of the first 29 amino acids of endogenous GHRH with four amino acid substitutions to improve stability and receptor binding....

Calculate CJC-1295 No-DAC dose →
MK-677
Growth Hormone & IGF

MK-677 (ibutamoren) is an orally active, non-peptide ghrelin receptor agonist (GHS-R1a) that stimulates GH release from the pituitary without requiring injection. It was developed by Merck and advanced through Phase II trials for growth hormone deficiency, muscle wasting, and fra...

Calculate MK-677 dose →
Key Parameters
Parameter CJC-1295 No-DAC MK-677
Category Growth Hormone & IGF Growth Hormone & IGF
Research Research Use Phase II (Discontinued)
Half-Life 30 minutes ~24 hours
Typical Dose 100–200 µg 10–25 mg
Frequency 2–3x daily Once daily
Route Subcutaneous Oral
FDA Status Not Approved Not Approved

Calculate doses for both

Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.

Calculate CJC-1295 No-DAC Calculate MK-677
Frequently Asked Questions
What is the difference between CJC-1295 No-DAC and MK-677?
CJC-1295 No-DAC: CJC-1295 No-DAC (also called Modified GRF 1-29 or Mod GRF) is a short-acting GHRH (Growth Hormone-Releasing Hormone) analog consisting of the first 29 amino acids of endogenous GHRH with four amino ac... MK-677: MK-677 (ibutamoren) is an orally active, non-peptide ghrelin receptor agonist (GHS-R1a) that stimulates GH release from the pituitary without requiring injection. It was developed by Merck and advance...
Which has a longer half-life, CJC-1295 No-DAC or MK-677?
CJC-1295 No-DAC half-life: 30 minutes. MK-677 half-life: ~24 hours.
Can you stack CJC-1295 No-DAC and MK-677?
CJC-1295 No-DAC and MK-677 are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.