Side-by-Side Comparison · 2026

CJC-1295 vs Sermorelin

CJC-1295 vs Sermorelin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

CJC-1295
Growth Hormone

CJC-1295 is a synthetic GHRH analog with a Drug Affinity Complex (DAC) that binds circulating albumin, extending half-life from 7 minutes to approximately 6-8 days. Enables once-weekly dosing with sustained GH elevation. Phase I/II clinical research status. WADA prohibited under ...

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Sermorelin
Growth Hormone

Sermorelin is a synthetic analog of the first 29 amino acids of endogenous GHRH, retaining full biological activity at the GHRH receptor. It was FDA approved (Geref) for GH deficiency in children from 1997 until its voluntary market withdrawal in 2008 for commercial reasons - not...

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Key Parameters
Parameter CJC-1295 Sermorelin
Category Growth Hormone Growth Hormone
Research Extensively Studied Extensively Studied
Half-Life ~6–8 days (with DAC) ~10–20 min
Typical Dose 1–2 mg 200–500 µg
Frequency Once weekly or twice weekly Once daily (bedtime)
Route Subcutaneous Subcutaneous
FDA Status Not Approved Compounding Only

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Frequently Asked Questions
What is the difference between CJC-1295 and Sermorelin?
CJC-1295: CJC-1295 is a synthetic GHRH analog with a Drug Affinity Complex (DAC) that binds circulating albumin, extending half-life from 7 minutes to approximately 6-8 days. Enables once-weekly dosing with sus... Sermorelin: Sermorelin is a synthetic analog of the first 29 amino acids of endogenous GHRH, retaining full biological activity at the GHRH receptor. It was FDA approved (Geref) for GH deficiency in children from...
Which has a longer half-life, CJC-1295 or Sermorelin?
CJC-1295 half-life: ~6–8 days (with DAC). Sermorelin half-life: ~10–20 min.
Can you stack CJC-1295 and Sermorelin?
CJC-1295 and Sermorelin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.