Side-by-Side Comparison · 2026

CJC-1295 vs Tesamorelin

CJC-1295 vs Tesamorelin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

CJC-1295
Growth Hormone

CJC-1295 is a synthetic GHRH analog with a Drug Affinity Complex (DAC) that binds circulating albumin, extending half-life from 7 minutes to approximately 6-8 days. Enables once-weekly dosing with sustained GH elevation. Phase I/II clinical research status. WADA prohibited under ...

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Tesamorelin
Growth Hormone

Tesamorelin is an FDA-approved synthetic GHRH analog (Egrifta) modified with trans-3-hexenoic acid to resist DPP-IV enzymatic cleavage, doubling its effective half-life. It restores pulsatile GH secretion and preferentially reduces visceral adipose tissue. Approved in 2010 for HI...

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Key Parameters
Parameter CJC-1295 Tesamorelin
Category Growth Hormone Growth Hormone
Research Extensively Studied FDA Approved
Half-Life ~6–8 days (with DAC) ~26–38 min
Typical Dose 1–2 mg 1–2 mg
Frequency Once weekly or twice weekly Once daily
Route Subcutaneous Subcutaneous
FDA Status Not Approved Approved

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Frequently Asked Questions
What is the difference between CJC-1295 and Tesamorelin?
CJC-1295: CJC-1295 is a synthetic GHRH analog with a Drug Affinity Complex (DAC) that binds circulating albumin, extending half-life from 7 minutes to approximately 6-8 days. Enables once-weekly dosing with sus... Tesamorelin: Tesamorelin is an FDA-approved synthetic GHRH analog (Egrifta) modified with trans-3-hexenoic acid to resist DPP-IV enzymatic cleavage, doubling its effective half-life. It restores pulsatile GH secre...
Which has a longer half-life, CJC-1295 or Tesamorelin?
CJC-1295 half-life: ~6–8 days (with DAC). Tesamorelin half-life: ~26–38 min.
Can you stack CJC-1295 and Tesamorelin?
CJC-1295 and Tesamorelin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.