Clavanin vs Gramicidin A — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?
Clavanin is a histidine-rich alpha-helical antimicrobial peptide originally isolated from the tunicate Styela clava. It is active at low pH, suggesting a role in intracellular killing of phagocytosed bacteria....
Calculate Clavanin dose →Gramicidin A is a 15-residue linear peptide antibiotic from Bacillus brevis, distinct from the cyclic gramicidin S despite sharing the same producer organism. Gramicidin A is the active component in Neosporin and other topical antibiotic combinations....
Calculate Gramicidin A dose →| Parameter | Clavanin | Gramicidin A |
|---|---|---|
| Category | Antimicrobial Peptide | Antimicrobial Peptide |
| Research | Preclinical | Approved (topical combination) |
| Half-Life | Short (minutes) | Hours (membrane-bound) |
| Typical Dose | N/A (research only) | Component of Neosporin and similar products |
| Frequency | N/A | As needed |
| Route | Topical / IV (research) | Topical (combination products) |
| FDA Status | Not approved | Approved (topical combination) |
Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.
For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.