Side-by-Side Comparison · 2026

Clavanin vs Omiganan

Clavanin vs Omiganan — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Clavanin
Antimicrobial Peptide

Clavanin is a histidine-rich alpha-helical antimicrobial peptide originally isolated from the tunicate Styela clava. It is active at low pH, suggesting a role in intracellular killing of phagocytosed bacteria....

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Omiganan
Antimicrobial Peptide

Omiganan (CLS001, MBI-226) is a synthetic analog of indolicidin, a bovine neutrophil AMP. It was developed for topical antimicrobial applications including acne vulgaris, catheter-site infection prevention, and rosacea....

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Key Parameters
Parameter Clavanin Omiganan
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Phase 3 (Completed)
Half-Life Short (minutes) Hours (topical)
Typical Dose N/A (research only) 1-3% gel
Frequency N/A Twice daily
Route Topical / IV (research) Topical gel/cream
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between Clavanin and Omiganan?
Clavanin: Clavanin is a histidine-rich alpha-helical antimicrobial peptide originally isolated from the tunicate Styela clava. It is active at low pH, suggesting a role in intracellular killing of phagocytosed ... Omiganan: Omiganan (CLS001, MBI-226) is a synthetic analog of indolicidin, a bovine neutrophil AMP. It was developed for topical antimicrobial applications including acne vulgaris, catheter-site infection preve...
Which has a longer half-life, Clavanin or Omiganan?
Clavanin half-life: Short (minutes). Omiganan half-life: Hours (topical).
Can you stack Clavanin and Omiganan?
Clavanin and Omiganan are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.