Side-by-Side Comparison · 2026

Cortexin vs N-Acetyl Selank Amidate

Cortexin vs N-Acetyl Selank Amidate — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Cortexin
Cognitive & Neurological

Cortexin is a polypeptide complex extracted from the cerebral cortex of pigs (porcine origin) that contains a mixture of low-molecular-weight neuropeptides, amino acids, and protein fractions. It is an approved drug in Russia, used clinically for stroke recovery, traumatic brain ...

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N-Acetyl Selank Amidate
Cognitive & Neurological

N-Acetyl Selank Amidate is a doubly-modified form of Selank (a synthetic heptapeptide based on tuftsin) with N-acetylation at the N-terminus and amidation at the C-terminus. These modifications extend enzymatic stability and CNS bioavailability, making it the highest-potency form...

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Key Parameters
Parameter Cortexin N-Acetyl Selank Amidate
Category Cognitive & Neurological Cognitive & Neurological
Research Approved (Russia/CIS) Research Use
Half-Life - ~6–8 hours (estimated; extended vs. standard Selank)
Typical Dose 10 mg 100–300 µg
Frequency Once daily Once or twice daily
Route Intramuscular Intranasal
FDA Status Not Approved Not Approved

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Frequently Asked Questions
What is the difference between Cortexin and N-Acetyl Selank Amidate?
Cortexin: Cortexin is a polypeptide complex extracted from the cerebral cortex of pigs (porcine origin) that contains a mixture of low-molecular-weight neuropeptides, amino acids, and protein fractions. It is a... N-Acetyl Selank Amidate: N-Acetyl Selank Amidate is a doubly-modified form of Selank (a synthetic heptapeptide based on tuftsin) with N-acetylation at the N-terminus and amidation at the C-terminus. These modifications extend...
Which has a longer half-life, Cortexin or N-Acetyl Selank Amidate?
Cortexin half-life: unknown. N-Acetyl Selank Amidate half-life: ~6–8 hours (estimated; extended vs. standard Selank).
Can you stack Cortexin and N-Acetyl Selank Amidate?
Cortexin and N-Acetyl Selank Amidate are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.