Side-by-Side Comparison · 2026

Cortistatin-14 vs Neurotensin

Cortistatin-14 vs Neurotensin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Cortistatin-14
Neuropeptide

Cortistatin-14 (CST-14) is an endogenous cyclic neuropeptide structurally related to somatostatin, sharing 11 of 14 amino acids with the somatostatin ring structure. Despite this similarity, cortistatin has distinct receptor binding and biological actions....

Calculate Cortistatin-14 dose →
Neurotensin
Neuropeptide

Neurotensin (NT) is a 13-amino acid neuropeptide widely distributed throughout the central and peripheral nervous systems, with high concentrations in the hypothalamus, nucleus accumbens, and gastrointestinal tract. Discovered in 1973, neurotensin modulates dopaminergic signaling...

Calculate Neurotensin dose →
Key Parameters
Parameter Cortistatin-14 Neurotensin
Category Neuropeptide Neuropeptide
Research Research Research
Half-Life Short (minutes) < 5 min (plasma)
Typical Dose 250-500 mcg (animal) 1-10 nmol/kg (animal)
Frequency Variable Variable
Route Subcutaneous, Intraperitoneal Subcutaneous, Intracerebroventricular
FDA Status Not approved Not approved

Calculate doses for both

Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.

Calculate Cortistatin-14 Calculate Neurotensin
Frequently Asked Questions
What is the difference between Cortistatin-14 and Neurotensin?
Cortistatin-14: Cortistatin-14 (CST-14) is an endogenous cyclic neuropeptide structurally related to somatostatin, sharing 11 of 14 amino acids with the somatostatin ring structure. Despite this similarity, cortistat... Neurotensin: Neurotensin (NT) is a 13-amino acid neuropeptide widely distributed throughout the central and peripheral nervous systems, with high concentrations in the hypothalamus, nucleus accumbens, and gastroin...
Which has a longer half-life, Cortistatin-14 or Neurotensin?
Cortistatin-14 half-life: Short (minutes). Neurotensin half-life: < 5 min (plasma).
Can you stack Cortistatin-14 and Neurotensin?
Cortistatin-14 and Neurotensin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.