Side-by-Side Comparison · 2026

CRH vs Vasopressin

CRH vs Vasopressin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

CRH
Hypothalamic Hormone

Corticotropin-releasing hormone (CRH, also CRF) is a 41-amino acid hypothalamic peptide first isolated by Vale et al. in 1981 after 40 years of searching....

Calculate CRH dose →
Vasopressin
Hypothalamic Hormone

Arginine vasopressin (AVP), also called antidiuretic hormone (ADH), is a 9-amino acid cyclic neuropeptide synthesized in hypothalamic magnocellular neurons and released from the posterior pituitary. AVP serves dual master roles: regulating water homeostasis via renal V2 receptors...

Calculate Vasopressin dose →
Key Parameters
Parameter CRH Vasopressin
Category Hypothalamic Hormone Hypothalamic Hormone
Research Clinical Clinical
Half-Life 60-73 min (plasma) 10-20 min (plasma)
Typical Dose 1 mcg/kg IV (CRH stimulation test) 0.01-0.04 U/min IV (vasopressor); 10-40 mcg intranasal
Frequency Single diagnostic dose or research protocol Variable
Route Intravenous (diagnostic), Subcutaneous Intravenous, Subcutaneous, Intranasal
FDA Status Approved (Acthrel, diagnostic use) Approved (vasopressor, diabetes insipidus)

Calculate doses for both

Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.

Calculate CRH Calculate Vasopressin
Frequently Asked Questions
What is the difference between CRH and Vasopressin?
CRH: Corticotropin-releasing hormone (CRH, also CRF) is a 41-amino acid hypothalamic peptide first isolated by Vale et al. in 1981 after 40 years of searching.... Vasopressin: Arginine vasopressin (AVP), also called antidiuretic hormone (ADH), is a 9-amino acid cyclic neuropeptide synthesized in hypothalamic magnocellular neurons and released from the posterior pituitary. A...
Which has a longer half-life, CRH or Vasopressin?
CRH half-life: 60-73 min (plasma). Vasopressin half-life: 10-20 min (plasma).
Can you stack CRH and Vasopressin?
CRH and Vasopressin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.