Side-by-Side Comparison · 2026

Dermaseptin vs Temporin

Dermaseptin vs Temporin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Dermaseptin
Antimicrobial Peptide

Dermaseptins are a family of 28-34 amino acid antimicrobial peptides first isolated from the skin of South American Phyllomedusa frogs. They are among the most potent broad-spectrum AMPs known, with activity against bacteria, fungi, protozoa, and viruses....

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Temporin
Antimicrobial Peptide

Temporins are a family of short (10-14 amino acid) cationic antimicrobial peptides isolated from the skin secretions of the European common frog (Rana temporaria). First described by Simmaco et al....

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Key Parameters
Parameter Dermaseptin Temporin
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Preclinical
Half-Life Minutes (proteolytic) Minutes (plasma)
Typical Dose N/A (research) Research only
Frequency N/A N/A
Route Topical / Parenteral (research) Topical, in vitro (research)
FDA Status Not approved No approval

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Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.

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Frequently Asked Questions
What is the difference between Dermaseptin and Temporin?
Dermaseptin: Dermaseptins are a family of 28-34 amino acid antimicrobial peptides first isolated from the skin of South American Phyllomedusa frogs. They are among the most potent broad-spectrum AMPs known, with a... Temporin: Temporins are a family of short (10-14 amino acid) cationic antimicrobial peptides isolated from the skin secretions of the European common frog (Rana temporaria). First described by Simmaco et al....
Which has a longer half-life, Dermaseptin or Temporin?
Dermaseptin half-life: Minutes (proteolytic). Temporin half-life: Minutes (plasma).
Can you stack Dermaseptin and Temporin?
Dermaseptin and Temporin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.