⚖ Head-to-Head · Injectable vs Oral GH

Hexarelin vs MK-677

Mechanism, half-life, dosing & research status compared side-by-side.

Hexarelin
Growth Hormone
Not Approved
Growth HormoneCardiacRecovery
Hexarelin (Examorelin) is the most potent GHRP in clinical research, producing the largest GH pulses per microgram of any peptide in its class. Its methylated tryptophan residue (2-MeTrp) compared to GHRP-6 accounts for …
Full Hexarelin profile →
MK-677
Growth Hormone & IGF
Not Approved
Growth HormoneOralNon-PeptideWADA ProhibitedPhase II
MK-677 (ibutamoren) is an orally active, non-peptide ghrelin receptor agonist (GHS-R1a) that stimulates GH release from the pituitary without requiring injection. It was developed by Merck and advanced through Phase II t…
Full MK-677 profile →
Technical Specs Comparison
MetricHexarelinMK-677
Research Status Extensively Studied Phase II (Discontinued)
Molecular Weight 887.1 Da 624.8 Da
Half-Life ~70 min ~24 hours
Peak Time ~30–60 min -
Typical Dose 100–200 µg 10–25 mg
Frequency 1–3× daily Once daily
Route Subcutaneous Oral
Amino Acids 6 -
WADA Status Prohibited Prohibited
FDA Status Not Approved Not Approved
Stack Compatibility & Key Differences
Both are active research compounds. See individual pages for full protocol data.
Frequently Asked Questions
What is the difference between Hexarelin and MK-677?
Hexarelin: Hexarelin (Examorelin) is the most potent GHRP in clinical research, producing the largest GH pulses per microgram of any peptide in its class. Its methylated tryptophan residue (2-MeTrp) compared to GHRP-6 accounts for … MK-677: MK-677 (ibutamoren) is an orally active, non-peptide ghrelin receptor agonist (GHS-R1a) that stimulates GH release from the pituitary without requiring injection. It was developed by Merck and advanced through Phase II t…
Can you stack Hexarelin and MK-677?
Both are active research compounds. See individual pages for full protocol data.
Which has a longer half-life, Hexarelin or MK-677?
Hexarelin half-life: ~70 min. MK-677 half-life: ~24 hours.
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Verified Scientific Data
All specifications on this page are sourced from peer-reviewed literature and primary research. Half-life values, dosing ranges, and mechanism data are cross-referenced against published studies. Last audited 2026-06-15.
● Peer-reviewed sources ● Audit timestamp: 2026-06-15 ● Data version: ASCEND Wiki 2026
Data sourced from ASCEND Wiki · Hexarelin profile · MK-677 profile · All comparisons
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