Side-by-Side Comparison · 2026

Intermedin vs Vasostatin

Intermedin vs Vasostatin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Intermedin
Cardiovascular Peptide

Intermedin (also called Adrenomedullin 2, AM2) is a 47-53 amino acid peptide belonging to the calcitonin gene-related peptide (CGRP)/adrenomedullin superfamily. Discovered in 2004, intermedin is widely expressed in the heart, lung, kidney, gut, and brain....

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Vasostatin
Cardiovascular Peptide

Vasostatin refers to the N-terminal fragments of chromogranin A (CgA), particularly CgA1-76 (Vasostatin-1) and CgA1-113 (Vasostatin-2), generated by proteolytic processing of the chromogranin A precursor. While catestatin (CgA352-372) is the C-terminal CgA fragment with anti-cate...

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Key Parameters
Parameter Intermedin Vasostatin
Category Cardiovascular Peptide Cardiovascular Peptide
Research Preclinical Research Preclinical Research
Half-Life ~15-30 minutes ~20-30 minutes (estimated)
Typical Dose 1-100 pmol/kg/min infusion (animal) 0.1-10 nmol/kg IV (animal)
Frequency Acute infusion Acute dosing
Route IV (research); SC in some studies IV (research)
FDA Status Research compound Research compound

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Frequently Asked Questions
What is the difference between Intermedin and Vasostatin?
Intermedin: Intermedin (also called Adrenomedullin 2, AM2) is a 47-53 amino acid peptide belonging to the calcitonin gene-related peptide (CGRP)/adrenomedullin superfamily. Discovered in 2004, intermedin is widel... Vasostatin: Vasostatin refers to the N-terminal fragments of chromogranin A (CgA), particularly CgA1-76 (Vasostatin-1) and CgA1-113 (Vasostatin-2), generated by proteolytic processing of the chromogranin A precur...
Which has a longer half-life, Intermedin or Vasostatin?
Intermedin half-life: ~15-30 minutes. Vasostatin half-life: ~20-30 minutes (estimated).
Can you stack Intermedin and Vasostatin?
Intermedin and Vasostatin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.