Side-by-Side Comparison · 2026

Kalata B1 vs Phylloseptin

Kalata B1 vs Phylloseptin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Kalata B1
Antimicrobial Peptide

Kalata B1 is the prototype cyclotide - a cyclic peptide with a head-to-tail backbone cyclization and three disulfide bonds forming a cystine knot topology. Isolated from the plant Oldenlandia affinis, which is traditionally used in Africa to accelerate childbirth (uterotonic use)...

Calculate Kalata B1 dose →
Phylloseptin
Antimicrobial Peptide

Phylloseptins are a family of short, C-terminally amidated alpha-helical antimicrobial peptides isolated from the skin secretions of South American Phyllomedusa frogs. Unlike the related dermaseptins from the same genus, phylloseptins are shorter (19 residues) and show a distinct...

Calculate Phylloseptin dose →
Key Parameters
Parameter Kalata B1 Phylloseptin
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Preclinical
Half-Life Hours (resistant to all proteases) Minutes (proteolytic)
Typical Dose N/A N/A
Frequency N/A N/A
Route Research only (oral stability under study) Research only
FDA Status Not approved Not approved

Calculate doses for both

Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.

Calculate Kalata B1 Calculate Phylloseptin
Frequently Asked Questions
What is the difference between Kalata B1 and Phylloseptin?
Kalata B1: Kalata B1 is the prototype cyclotide - a cyclic peptide with a head-to-tail backbone cyclization and three disulfide bonds forming a cystine knot topology. Isolated from the plant Oldenlandia affinis,... Phylloseptin: Phylloseptins are a family of short, C-terminally amidated alpha-helical antimicrobial peptides isolated from the skin secretions of South American Phyllomedusa frogs. Unlike the related dermaseptins ...
Which has a longer half-life, Kalata B1 or Phylloseptin?
Kalata B1 half-life: Hours (resistant to all proteases). Phylloseptin half-life: Minutes (proteolytic).
Can you stack Kalata B1 and Phylloseptin?
Kalata B1 and Phylloseptin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.