Side-by-Side Comparison · 2026

Kalata B1 vs Plectasin

Kalata B1 vs Plectasin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Kalata B1
Antimicrobial Peptide

Kalata B1 is the prototype cyclotide - a cyclic peptide with a head-to-tail backbone cyclization and three disulfide bonds forming a cystine knot topology. Isolated from the plant Oldenlandia affinis, which is traditionally used in Africa to accelerate childbirth (uterotonic use)...

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Plectasin
Antimicrobial Peptide

Plectasin is a 40-residue defensin-like antimicrobial peptide discovered in 2005 from the saprophytic fungus Pseudoplectania nigrella. It was the first AMP isolated from a fungal organism....

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Key Parameters
Parameter Kalata B1 Plectasin
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Preclinical
Half-Life Hours (resistant to all proteases) Hours (disulfide stabilized)
Typical Dose N/A N/A
Frequency N/A N/A
Route Research only (oral stability under study) Research only
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between Kalata B1 and Plectasin?
Kalata B1: Kalata B1 is the prototype cyclotide - a cyclic peptide with a head-to-tail backbone cyclization and three disulfide bonds forming a cystine knot topology. Isolated from the plant Oldenlandia affinis,... Plectasin: Plectasin is a 40-residue defensin-like antimicrobial peptide discovered in 2005 from the saprophytic fungus Pseudoplectania nigrella. It was the first AMP isolated from a fungal organism....
Which has a longer half-life, Kalata B1 or Plectasin?
Kalata B1 half-life: Hours (resistant to all proteases). Plectasin half-life: Hours (disulfide stabilized).
Can you stack Kalata B1 and Plectasin?
Kalata B1 and Plectasin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.