Side-by-Side Comparison · 2026

Kalata B1 vs Tigerinin

Kalata B1 vs Tigerinin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Kalata B1
Antimicrobial Peptide

Kalata B1 is the prototype cyclotide - a cyclic peptide with a head-to-tail backbone cyclization and three disulfide bonds forming a cystine knot topology. Isolated from the plant Oldenlandia affinis, which is traditionally used in Africa to accelerate childbirth (uterotonic use)...

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Tigerinin
Antimicrobial Peptide

Tigerinin peptides are isolated from the skin of the Indian skipper frog Hoplobatrachus tigerinus. They are among the shortest naturally occurring AMPs....

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Key Parameters
Parameter Kalata B1 Tigerinin
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Preclinical
Half-Life Hours (resistant to all proteases) Minutes (proteolytic)
Typical Dose N/A N/A
Frequency N/A N/A
Route Research only (oral stability under study) Research only
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between Kalata B1 and Tigerinin?
Kalata B1: Kalata B1 is the prototype cyclotide - a cyclic peptide with a head-to-tail backbone cyclization and three disulfide bonds forming a cystine knot topology. Isolated from the plant Oldenlandia affinis,... Tigerinin: Tigerinin peptides are isolated from the skin of the Indian skipper frog Hoplobatrachus tigerinus. They are among the shortest naturally occurring AMPs....
Which has a longer half-life, Kalata B1 or Tigerinin?
Kalata B1 half-life: Hours (resistant to all proteases). Tigerinin half-life: Minutes (proteolytic).
Can you stack Kalata B1 and Tigerinin?
Kalata B1 and Tigerinin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.