Side-by-Side Comparison · 2026

Kassinin vs Physalaemin

Kassinin vs Physalaemin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Kassinin
Neuropeptide / Tachykinin

Kassinin is a tachykinin peptide isolated from the skin of the African frog Kassina senegalensis. It preferentially activates NK2 receptors, distinguishing it from physalaemin (NK1) and making it valuable in delineating NK2 receptor pharmacology....

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Physalaemin
Neuropeptide / Tachykinin

Physalaemin is an 11-residue tachykinin peptide first isolated from the skin of the South American frog Physalaemus fuscumaculatus. It shares the conserved tachykinin C-terminal sequence Phe-X-Gly-Leu-Met-NH2 with substance P, eledoisin, and kassinin....

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Key Parameters
Parameter Kassinin Physalaemin
Category Neuropeptide / Tachykinin Neuropeptide / Tachykinin
Research Preclinical Preclinical
Half-Life Short (minutes) Short (minutes)
Typical Dose N/A (research) N/A (research)
Frequency N/A N/A
Route IV / SC (research) IV / SC (research)
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between Kassinin and Physalaemin?
Kassinin: Kassinin is a tachykinin peptide isolated from the skin of the African frog Kassina senegalensis. It preferentially activates NK2 receptors, distinguishing it from physalaemin (NK1) and making it valu... Physalaemin: Physalaemin is an 11-residue tachykinin peptide first isolated from the skin of the South American frog Physalaemus fuscumaculatus. It shares the conserved tachykinin C-terminal sequence Phe-X-Gly-Leu...
Which has a longer half-life, Kassinin or Physalaemin?
Kassinin half-life: Short (minutes). Physalaemin half-life: Short (minutes).
Can you stack Kassinin and Physalaemin?
Kassinin and Physalaemin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.