L-Carnitine vs Methylcobalamin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?
L-Carnitine (Levocarnitine) is a naturally occurring quaternary ammonium compound synthesized endogenously from the amino acids lysine and methionine, primarily in the liver and kidneys. Its defining biological role is transporting long-chain fatty acids across the inner mitochon...
Calculate L-Carnitine dose →Methylcobalamin is the biologically active, methyl-group-carrying form of Vitamin B12 (cobalamin). Unlike cyanocobalamin (the synthetic form found in most oral supplements), methylcobalamin is the form that functions directly in the central nervous system and participates in the ...
Calculate Methylcobalamin dose →| Parameter | L-Carnitine | Methylcobalamin |
|---|---|---|
| Category | Mitochondrial & Longevity | Mitochondrial & Longevity |
| Research | FDA Approved (deficiency indications) | FDA Approved (deficiency indications) |
| Half-Life | ~17.4 hours (terminal elimination) | ~6 days (serum) |
| Typical Dose | 500–2000 mg | 1000 mcg (1 mg) |
| Frequency | Daily or 3x/week | Weekly or twice weekly |
| Route | Intravenous / Intramuscular | Subcutaneous / Intramuscular |
| FDA Status | FDA Approved | FDA Approved |
Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.
For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.