Side-by-Side Comparison · 2026

Lactoferricin vs Omiganan

Lactoferricin vs Omiganan — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Lactoferricin
Antimicrobial Peptide

Lactoferricin B (LfcinB) is a 25-residue antimicrobial peptide released from the N-terminal region of bovine lactoferrin by pepsin digestion in the stomach. The core hexapeptide RRWQWR contains the minimal active unit....

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Omiganan
Antimicrobial Peptide

Omiganan (CLS001, MBI-226) is a synthetic analog of indolicidin, a bovine neutrophil AMP. It was developed for topical antimicrobial applications including acne vulgaris, catheter-site infection prevention, and rosacea....

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Key Parameters
Parameter Lactoferricin Omiganan
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Phase 3 (Completed)
Half-Life Minutes (proteolytic) Hours (topical)
Typical Dose N/A 1-3% gel
Frequency N/A Twice daily
Route Research only Topical gel/cream
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between Lactoferricin and Omiganan?
Lactoferricin: Lactoferricin B (LfcinB) is a 25-residue antimicrobial peptide released from the N-terminal region of bovine lactoferrin by pepsin digestion in the stomach. The core hexapeptide RRWQWR contains the mi... Omiganan: Omiganan (CLS001, MBI-226) is a synthetic analog of indolicidin, a bovine neutrophil AMP. It was developed for topical antimicrobial applications including acne vulgaris, catheter-site infection preve...
Which has a longer half-life, Lactoferricin or Omiganan?
Lactoferricin half-life: Minutes (proteolytic). Omiganan half-life: Hours (topical).
Can you stack Lactoferricin and Omiganan?
Lactoferricin and Omiganan are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.