Side-by-Side Comparison · 2026

Maximin vs Pexiganan

Maximin vs Pexiganan — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Maximin
Antimicrobial Peptide

Maximins are a large and diverse family of antimicrobial and neuroactive peptides isolated from the skin and brain of the Chinese firebelly toad Bombina maxima. Maximins are notable for containing D-amino acid residues in specific positions, a rare post-translational modification...

Calculate Maximin dose →
Pexiganan
Antimicrobial Peptide

Pexiganan (MSI-78) is a synthetic analog of magainin-2, optimized for enhanced broad-spectrum antimicrobial activity and reduced hemolytic toxicity. It was developed by Magainin Pharmaceuticals (later Genaera) as a topical treatment for mildly infected diabetic foot ulcers....

Calculate Pexiganan dose →
Key Parameters
Parameter Maximin Pexiganan
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Phase 3 (Failed 1999)
Half-Life Hours (protease-resistant D-amino acids) Hours (topical)
Typical Dose N/A 0.8% cream topically
Frequency N/A Twice daily
Route Research only Topical cream
FDA Status Not approved Not approved (failed Phase 3)

Calculate doses for both

Use ASCEND's free reconstitution calculator to get exact syringe draw amounts for your vial.

Calculate Maximin Calculate Pexiganan
Frequently Asked Questions
What is the difference between Maximin and Pexiganan?
Maximin: Maximins are a large and diverse family of antimicrobial and neuroactive peptides isolated from the skin and brain of the Chinese firebelly toad Bombina maxima. Maximins are notable for containing D-a... Pexiganan: Pexiganan (MSI-78) is a synthetic analog of magainin-2, optimized for enhanced broad-spectrum antimicrobial activity and reduced hemolytic toxicity. It was developed by Magainin Pharmaceuticals (later...
Which has a longer half-life, Maximin or Pexiganan?
Maximin half-life: Hours (protease-resistant D-amino acids). Pexiganan half-life: Hours (topical).
Can you stack Maximin and Pexiganan?
Maximin and Pexiganan are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.