Side-by-Side Comparison · 2026

Maximin vs PGLa

Maximin vs PGLa — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Maximin
Antimicrobial Peptide

Maximins are a large and diverse family of antimicrobial and neuroactive peptides isolated from the skin and brain of the Chinese firebelly toad Bombina maxima. Maximins are notable for containing D-amino acid residues in specific positions, a rare post-translational modification...

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PGLa
Antimicrobial Peptide

PGLa is a 22-residue alpha-helical antimicrobial peptide co-isolated with magainin-2 from the skin of the African clawed frog Xenopus laevis. Individually, PGLa and magainin-2 show modest antimicrobial activity, but when combined at equimolar ratios, they exhibit synergistic kill...

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Key Parameters
Parameter Maximin PGLa
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Preclinical
Half-Life Hours (protease-resistant D-amino acids) Minutes (proteolytic)
Typical Dose N/A N/A
Frequency N/A N/A
Route Research only Research only
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between Maximin and PGLa?
Maximin: Maximins are a large and diverse family of antimicrobial and neuroactive peptides isolated from the skin and brain of the Chinese firebelly toad Bombina maxima. Maximins are notable for containing D-a... PGLa: PGLa is a 22-residue alpha-helical antimicrobial peptide co-isolated with magainin-2 from the skin of the African clawed frog Xenopus laevis. Individually, PGLa and magainin-2 show modest antimicrobia...
Which has a longer half-life, Maximin or PGLa?
Maximin half-life: Hours (protease-resistant D-amino acids). PGLa half-life: Minutes (proteolytic).
Can you stack Maximin and PGLa?
Maximin and PGLa are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.