Side-by-Side Comparison · 2026

Maximin vs PR-39

Maximin vs PR-39 — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Maximin
Antimicrobial Peptide

Maximins are a large and diverse family of antimicrobial and neuroactive peptides isolated from the skin and brain of the Chinese firebelly toad Bombina maxima. Maximins are notable for containing D-amino acid residues in specific positions, a rare post-translational modification...

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PR-39
Antimicrobial Peptide

PR-39 is a 39-residue proline- and arginine-rich antimicrobial peptide from porcine neutrophil granules. Unlike classical membrane-disrupting AMPs, PR-39 kills bacteria intracellularly by inhibiting DNA and protein synthesis....

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Key Parameters
Parameter Maximin PR-39
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Preclinical
Half-Life Hours (protease-resistant D-amino acids) Minutes (proteolytic)
Typical Dose N/A N/A
Frequency N/A N/A
Route Research only Research only
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between Maximin and PR-39?
Maximin: Maximins are a large and diverse family of antimicrobial and neuroactive peptides isolated from the skin and brain of the Chinese firebelly toad Bombina maxima. Maximins are notable for containing D-a... PR-39: PR-39 is a 39-residue proline- and arginine-rich antimicrobial peptide from porcine neutrophil granules. Unlike classical membrane-disrupting AMPs, PR-39 kills bacteria intracellularly by inhibiting D...
Which has a longer half-life, Maximin or PR-39?
Maximin half-life: Hours (protease-resistant D-amino acids). PR-39 half-life: Minutes (proteolytic).
Can you stack Maximin and PR-39?
Maximin and PR-39 are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.