Side-by-Side Comparison · 2026

Neuromedin N vs Relaxin-3

Neuromedin N vs Relaxin-3 — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Neuromedin N
Neuropeptide

Neuromedin N (NMN) is a hexapeptide co-encoded in the same gene as neurotensin and processed from the same precursor protein. Its C-terminal sequence is structurally related to the active C-terminal fragment of neurotensin, sharing its Ile-Leu C-terminal dipeptide....

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Relaxin-3
Neuropeptide

Relaxin-3 (also called INSL7) is the most ancient member of the insulin/relaxin superfamily and is expressed predominantly in the nucleus incertus (NI) of the brainstem, a structure implicated in stress, arousal, and hippocampal theta rhythm generation. Unlike relaxin-1 and relax...

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Key Parameters
Parameter Neuromedin N Relaxin-3
Category Neuropeptide Neuropeptide
Research Preclinical Preclinical Research
Half-Life Very short (seconds-minutes) ~30-60 minutes (estimated)
Typical Dose N/A (preclinical) 100-500 pmol ICV; 1-3 nmol/kg SC
Frequency N/A Single or twice daily (preclinical)
Route ICV / IV (research) ICV, SC (preclinical)
FDA Status Not approved Research compound

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Frequently Asked Questions
What is the difference between Neuromedin N and Relaxin-3?
Neuromedin N: Neuromedin N (NMN) is a hexapeptide co-encoded in the same gene as neurotensin and processed from the same precursor protein. Its C-terminal sequence is structurally related to the active C-terminal f... Relaxin-3: Relaxin-3 (also called INSL7) is the most ancient member of the insulin/relaxin superfamily and is expressed predominantly in the nucleus incertus (NI) of the brainstem, a structure implicated in stre...
Which has a longer half-life, Neuromedin N or Relaxin-3?
Neuromedin N half-life: Very short (seconds-minutes). Relaxin-3 half-life: ~30-60 minutes (estimated).
Can you stack Neuromedin N and Relaxin-3?
Neuromedin N and Relaxin-3 are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.