Side-by-Side Comparison · 2026

Neuromedin U vs Relaxin-3

Neuromedin U vs Relaxin-3 — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Neuromedin U
Neuropeptide

Neuromedin U (NMU) is a neuropeptide first isolated from porcine spinal cord and named for its ability to contract the uterus. Two bioactive forms exist in humans: the shorter NMU-23 and the predominant NMU-25, both C-terminally amidated....

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Relaxin-3
Neuropeptide

Relaxin-3 (also called INSL7) is the most ancient member of the insulin/relaxin superfamily and is expressed predominantly in the nucleus incertus (NI) of the brainstem, a structure implicated in stress, arousal, and hippocampal theta rhythm generation. Unlike relaxin-1 and relax...

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Key Parameters
Parameter Neuromedin U Relaxin-3
Category Neuropeptide Neuropeptide
Research Research Preclinical Research
Half-Life Short (minutes) ~30-60 minutes (estimated)
Typical Dose 1-10 nmol/kg (animal) 100-500 pmol ICV; 1-3 nmol/kg SC
Frequency Variable Single or twice daily (preclinical)
Route Subcutaneous, Intracerebroventricular ICV, SC (preclinical)
FDA Status Not approved Research compound

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Frequently Asked Questions
What is the difference between Neuromedin U and Relaxin-3?
Neuromedin U: Neuromedin U (NMU) is a neuropeptide first isolated from porcine spinal cord and named for its ability to contract the uterus. Two bioactive forms exist in humans: the shorter NMU-23 and the predomina... Relaxin-3: Relaxin-3 (also called INSL7) is the most ancient member of the insulin/relaxin superfamily and is expressed predominantly in the nucleus incertus (NI) of the brainstem, a structure implicated in stre...
Which has a longer half-life, Neuromedin U or Relaxin-3?
Neuromedin U half-life: Short (minutes). Relaxin-3 half-life: ~30-60 minutes (estimated).
Can you stack Neuromedin U and Relaxin-3?
Neuromedin U and Relaxin-3 are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.