Side-by-Side Comparison · 2026

PGLa vs Tigerinin

PGLa vs Tigerinin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

PGLa
Antimicrobial Peptide

PGLa is a 22-residue alpha-helical antimicrobial peptide co-isolated with magainin-2 from the skin of the African clawed frog Xenopus laevis. Individually, PGLa and magainin-2 show modest antimicrobial activity, but when combined at equimolar ratios, they exhibit synergistic kill...

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Tigerinin
Antimicrobial Peptide

Tigerinin peptides are isolated from the skin of the Indian skipper frog Hoplobatrachus tigerinus. They are among the shortest naturally occurring AMPs....

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Key Parameters
Parameter PGLa Tigerinin
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Preclinical
Half-Life Minutes (proteolytic) Minutes (proteolytic)
Typical Dose N/A N/A
Frequency N/A N/A
Route Research only Research only
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between PGLa and Tigerinin?
PGLa: PGLa is a 22-residue alpha-helical antimicrobial peptide co-isolated with magainin-2 from the skin of the African clawed frog Xenopus laevis. Individually, PGLa and magainin-2 show modest antimicrobia... Tigerinin: Tigerinin peptides are isolated from the skin of the Indian skipper frog Hoplobatrachus tigerinus. They are among the shortest naturally occurring AMPs....
Which has a longer half-life, PGLa or Tigerinin?
PGLa half-life: Minutes (proteolytic). Tigerinin half-life: Minutes (proteolytic).
Can you stack PGLa and Tigerinin?
PGLa and Tigerinin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.