Side-by-Side Comparison · 2026

Phylloseptin vs Tigerinin

Phylloseptin vs Tigerinin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

Phylloseptin
Antimicrobial Peptide

Phylloseptins are a family of short, C-terminally amidated alpha-helical antimicrobial peptides isolated from the skin secretions of South American Phyllomedusa frogs. Unlike the related dermaseptins from the same genus, phylloseptins are shorter (19 residues) and show a distinct...

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Tigerinin
Antimicrobial Peptide

Tigerinin peptides are isolated from the skin of the Indian skipper frog Hoplobatrachus tigerinus. They are among the shortest naturally occurring AMPs....

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Key Parameters
Parameter Phylloseptin Tigerinin
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Preclinical
Half-Life Minutes (proteolytic) Minutes (proteolytic)
Typical Dose N/A N/A
Frequency N/A N/A
Route Research only Research only
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between Phylloseptin and Tigerinin?
Phylloseptin: Phylloseptins are a family of short, C-terminally amidated alpha-helical antimicrobial peptides isolated from the skin secretions of South American Phyllomedusa frogs. Unlike the related dermaseptins ... Tigerinin: Tigerinin peptides are isolated from the skin of the Indian skipper frog Hoplobatrachus tigerinus. They are among the shortest naturally occurring AMPs....
Which has a longer half-life, Phylloseptin or Tigerinin?
Phylloseptin half-life: Minutes (proteolytic). Tigerinin half-life: Minutes (proteolytic).
Can you stack Phylloseptin and Tigerinin?
Phylloseptin and Tigerinin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.