Side-by-Side Comparison · 2026

PR-39 vs Tigerinin

PR-39 vs Tigerinin — mechanism, half-life, dosing, and research status compared. Which is right for your protocol?

PR-39
Antimicrobial Peptide

PR-39 is a 39-residue proline- and arginine-rich antimicrobial peptide from porcine neutrophil granules. Unlike classical membrane-disrupting AMPs, PR-39 kills bacteria intracellularly by inhibiting DNA and protein synthesis....

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Tigerinin
Antimicrobial Peptide

Tigerinin peptides are isolated from the skin of the Indian skipper frog Hoplobatrachus tigerinus. They are among the shortest naturally occurring AMPs....

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Key Parameters
Parameter PR-39 Tigerinin
Category Antimicrobial Peptide Antimicrobial Peptide
Research Preclinical Preclinical
Half-Life Minutes (proteolytic) Minutes (proteolytic)
Typical Dose N/A N/A
Frequency N/A N/A
Route Research only Research only
FDA Status Not approved Not approved

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Frequently Asked Questions
What is the difference between PR-39 and Tigerinin?
PR-39: PR-39 is a 39-residue proline- and arginine-rich antimicrobial peptide from porcine neutrophil granules. Unlike classical membrane-disrupting AMPs, PR-39 kills bacteria intracellularly by inhibiting D... Tigerinin: Tigerinin peptides are isolated from the skin of the Indian skipper frog Hoplobatrachus tigerinus. They are among the shortest naturally occurring AMPs....
Which has a longer half-life, PR-39 or Tigerinin?
PR-39 half-life: Minutes (proteolytic). Tigerinin half-life: Minutes (proteolytic).
Can you stack PR-39 and Tigerinin?
PR-39 and Tigerinin are in the same category and used together in research protocols. Always consult relevant literature and follow appropriate guidelines.

For research use only. Not medical advice. ASCEND does not conduct or endorse any specific research protocol. Always consult relevant scientific literature and regulatory guidelines.