MK-677
Growth Hormone & IGF
Not Approved
Growth HormoneOralNon-PeptideWADA ProhibitedPhase II
MK-677 (ibutamoren) is an orally active, non-peptide ghrelin receptor agonist (GHS-R1a) that stimulates GH release from the pituitary without requiring injection. It was developed by Merck and advanced through Phase II t…
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Sermorelin
Growth Hormone
Compounding Only
Growth HormoneAnti-agingRecoverySleep
Sermorelin is a synthetic analog of the first 29 amino acids of endogenous GHRH, retaining full biological activity at the GHRH receptor. It was FDA approved (Geref) for GH deficiency in children from 1997 until its volu…
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Stack Compatibility & Key Differences
Both are active research compounds. See individual pages for full protocol data.
Frequently Asked Questions
What is the difference between MK-677 and Sermorelin?
MK-677: MK-677 (ibutamoren) is an orally active, non-peptide ghrelin receptor agonist (GHS-R1a) that stimulates GH release from the pituitary without requiring injection. It was developed by Merck and advanced through Phase II t… Sermorelin: Sermorelin is a synthetic analog of the first 29 amino acids of endogenous GHRH, retaining full biological activity at the GHRH receptor. It was FDA approved (Geref) for GH deficiency in children from 1997 until its volu…
Can you stack MK-677 and Sermorelin?
Both are active research compounds. See individual pages for full protocol data.
Which has a longer half-life, MK-677 or Sermorelin?
MK-677 half-life: ~24 hours. Sermorelin half-life: ~10–20 min.