Growth Hormone
Sermorelin Dosing & Reconstitution Calculator
GHRH analog stimulating pituitary growth hormone release for anti-aging protocols.
TL;DR - Sermorelin is a growth hormone peptide with a typical starting dose of 300 µg. For a 5 mg vial, add 2 mL bacteriostatic water to yield 2500 µg/mL.
300 µg
Start Dose
5 mg
Vial
2 mL
BAC Water
2500
µg/mL
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Frequently Asked
How do I reconstitute Sermorelin?
Add 2 mL of bacteriostatic water to a 5 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 2500 µg/mL.
What is the recommended dose of Sermorelin?
A typical research dose is 300 µg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a Sermorelin vial?
A 5 mg vial reconstituted with 2 mL BAC water yields approximately 16 doses at 300 µg each.
How many IU is 300 µg of Sermorelin on a syringe?
With a 5 mg vial reconstituted in 2 mL bacteriostatic water, the concentration is 2500 µg/mL. For a 300 µg dose: Volume = 300 µg ÷ 2500 µg/mL = 0.12 mL. Draw to the 12 line on a 100-unit insulin syringe. You can adjust these values in the ASCEND calculator for any vial size.
What does a Sermorelin dosage calculator do?
A Sermorelin dosage calculator converts your vial size and BAC water volume into an exact syringe draw in IU. Enter your vial strength (5 mg), reconstitution volume (2 mL), and target dose to get the precise line to draw on an insulin syringe.
What is the Sermorelin reconstitution calculator formula?
Draw volume (mL) = Dose (µg) divided by Concentration (µg/mL). For a 5 mg vial with 2 mL BAC water: concentration = 2500 µg/mL. For a 300 µg dose, the ASCEND calculator gives the exact IU line on your syringe instantly.
Peptide Intelligence
What is the half-life of Sermorelin?
Sermorelin has a very short half-life of under 10 minutes due to rapid plasma degradation by endopeptidases. Daily subcutaneous injection (typically pre-sleep) is the standard research protocol. Its short half-life limits GH elevation to a brief pulsatile burst.
How does Sermorelin compare to Tesamorelin?
Both are GHRH analogs, but Tesamorelin has a longer half-life (~26 min) and is FDA-approved for HIV lipodystrophy. Sermorelin is the original GHRH fragment (1-29) and was previously FDA-approved for pediatric GH deficiency. Tesamorelin is considered more stable in solution.
Is Sermorelin typically used alone or in combination?
Sermorelin is often combined with Ipamorelin or GHRP-2 to amplify GH release. The combination of a GHRH analog with a ghrelin mimetic acts synergistically on the pituitary. Some protocols use Sermorelin alone at bedtime for anti-aging purposes.
Also Explore
Research Guides
Bacteriostatic Water Guide
What it is & why it matters for reconstitution
How Much BAC Water for Sermorelin?
5 mg vial reconstitution recipe + concentration table
Sermorelin on Insulin Syringe
300 µg draw on 30u / 50u / 100u syringes
Sermorelin + Ipamorelin Stack
Short-acting GHRH + clean GH pulse
Insulin Syringe Guide
Choosing the right gauge & volume for your draw
Multi-Lab Verification Standard
How ASCEND ensures dosing accuracy
Cite This Calculator