Selective growth hormone secretagogue with minimal cortisol and prolactin elevation.
TL;DR — Ipamorelin is a growth hormone peptide with a typical starting dose of 300 µg. For a 5 mg vial, add 2 mL bacteriostatic water to yield 2500 µg/mL.
Add 2 mL of bacteriostatic water to a 5 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 2500 µg/mL.
What is the recommended dose of Ipamorelin?
A typical research dose is 300 µg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a Ipamorelin vial?
A 5 mg vial reconstituted with 2 mL BAC water yields approximately 16 doses at 300 µg each.
Peptide Intelligence
What is the half-life of Ipamorelin?
Ipamorelin has a short half-life of approximately 2 hours after subcutaneous injection, making it suitable for pulsatile GH release mimicry. Most protocols use 2–3 injections daily, often upon waking, pre-workout, and pre-sleep.
Why is Ipamorelin considered selective compared to other GHRPs?
Ipamorelin selectively stimulates GH release with minimal effect on cortisol, prolactin, or ACTH, unlike GHRP-2 and GHRP-6 which significantly elevate cortisol and prolactin. This selectivity makes Ipamorelin better tolerated in long-term protocols.
Is Ipamorelin typically stacked with a GHRH peptide?
Ipamorelin is most commonly stacked with CJC-1295 (No DAC) in a 1:1 ratio. CJC-1295 activates GHRH receptors while Ipamorelin activates ghrelin receptors, producing synergistic GH release that exceeds either peptide alone.