Growth Hormone

CJC-1295 (With DAC) Dosing & Reconstitution Calculator

Long-acting GHRH analog with drug affinity complex for sustained GH elevation.

TL;DR - CJC-1295 (With DAC) is a growth hormone peptide with a typical starting dose of 2 mg. For a 5 mg vial, add 1 mL bacteriostatic water to yield 5 mg/mL.
2 mg
Start Dose
5 mg
Vial
1 mL
BAC Water
5
mg/mL
2 mg draw on a 100-unit insulin syringe
010203040506070809010040 IUascendpeptide.org
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Frequently Asked
How do I reconstitute CJC-1295 (With DAC)?
Add 1 mL of bacteriostatic water to a 5 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 5 mg/mL.
What is the recommended dose of CJC-1295 (With DAC)?
A typical research dose is 2 mg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a CJC-1295 (With DAC) vial?
A 5 mg vial reconstituted with 1 mL BAC water yields approximately 2 doses at 2 mg each.
How many IU is 2 mg of CJC-1295 (With DAC) on a syringe?
With a 5 mg vial reconstituted in 1 mL bacteriostatic water, the concentration is 5 mg/mL. For a 2 mg dose: Volume = 2 mg ÷ 5 mg/mL = 0.4 mL. Draw to the 40 line on a 100-unit insulin syringe. You can adjust these values in the ASCEND calculator for any vial size.
What does a CJC-1295 (With DAC) dosage calculator do?
A CJC-1295 (With DAC) dosage calculator converts your vial size and BAC water volume into an exact syringe draw in IU. Enter your vial strength (5 mg), reconstitution volume (1 mL), and target dose to get the precise line to draw on an insulin syringe.
What is the CJC-1295 (With DAC) reconstitution calculator formula?
Draw volume (mL) = Dose (mg) divided by Concentration (mg/mL). For a 5 mg vial with 1 mL BAC water: concentration = 5 mg/mL. For a 2 mg dose, the ASCEND calculator gives the exact IU line on your syringe instantly.
Peptide Intelligence
What is the half-life of CJC-1295 with DAC?
CJC-1295 with DAC has a half-life of approximately 6–8 days due to its Drug Affinity Complex, which enables covalent binding to albumin. This allows once or twice-weekly dosing for sustained GH elevation, unlike the pulsatile No DAC version.
Does CJC-1295 with DAC blunt natural GH pulsatility?
By maintaining continuously elevated GHRH stimulation, CJC-1295 with DAC can suppress natural pulsatile GH rhythm. Some researchers prefer the No DAC version to preserve pulsatility. Extended use may also cause GH receptor desensitization over time.
Can CJC-1295 with DAC be stacked with Ipamorelin?
Yes, this is a common combination. Ipamorelin (short-acting ghrelin receptor agonist) is taken 2–3 times daily for pulsatile GH release, while CJC-1295 with DAC provides a sustained GHRH baseline. The combination produces synergistic GH release in research models.
Primary Sources
DAC-GRF Phase 1/2 (JCEM 2006)
Data last reviewed 2026-06-03 · Methodology →
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