Growth Hormone

CJC-1295 (With DAC) Dosing & Reconstitution Calculator

Long-acting GHRH analog with drug affinity complex for sustained GH elevation.

TL;DR — CJC-1295 (With DAC) is a growth hormone peptide with a typical starting dose of 2 mg. For a 5 mg vial, add 1 mL bacteriostatic water to yield 5 mg/mL.
2 mg
Start Dose
5 mg
Vial
1 mL
BAC Water
5
mg/mL
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Frequently Asked
How do I reconstitute CJC-1295 (With DAC)?
Add 1 mL of bacteriostatic water to a 5 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 5 mg/mL.
What is the recommended dose of CJC-1295 (With DAC)?
A typical research dose is 2 mg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a CJC-1295 (With DAC) vial?
A 5 mg vial reconstituted with 1 mL BAC water yields approximately 2 doses at 2 mg each.
Peptide Intelligence
What is the half-life of CJC-1295 with DAC?
CJC-1295 with DAC has a half-life of approximately 6–8 days due to its Drug Affinity Complex, which enables covalent binding to albumin. This allows once or twice-weekly dosing for sustained GH elevation, unlike the pulsatile No DAC version.
Does CJC-1295 with DAC blunt natural GH pulsatility?
By maintaining continuously elevated GHRH stimulation, CJC-1295 with DAC can suppress natural pulsatile GH rhythm. Some researchers prefer the No DAC version to preserve pulsatility. Extended use may also cause GH receptor desensitization over time.
Can CJC-1295 with DAC be stacked with Ipamorelin?
Yes, this is a common combination. Ipamorelin (short-acting ghrelin receptor agonist) is taken 2–3 times daily for pulsatile GH release, while CJC-1295 with DAC provides a sustained GHRH baseline. The combination produces synergistic GH release in research models.
Recommended Next Step
GH Pulse Stack
Ipamorelin provides pulsatile ghrelin receptor activation to complement the sustained GHRH stimulation from CJC-1295 with DAC.
Open Ipamorelin Calculator →
Also Explore
Primary Sources
DAC-GRF Phase 1/2 (JCEM 2006)
Data last reviewed 2026-04-19 · Methodology →
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