ASCEND is a peptide dosing calculator. Where available, presets are sourced directly from published clinical trial data, not forum posts or guesswork. Independent lab verification confirms what's actually in each vial.
Where available, dosing presets are built from primary literature: published Phase 2 and Phase 3 trial protocols, FDA pharmacology reviews, and peer-reviewed pharmacokinetic studies. When multiple sources conflict, we favor the most conservative, well-powered study.
Reconstitution volumes are calculated to maximize measurement precision on standard U-100 insulin syringes. We flag doses that require splitting across multiple vials.
Certificate of Analysis data on ASCEND is independently analyzed and verified by credentialed laboratory scientists at BTLabs and Janoshik: real humans with real credentials, not AI-generated summaries. These are examples of the analysts and scientists involved in verification - the full team spans multiple institutions.
Peptide reconstitution math is deceptively simple to get wrong. A researcher mixing a 5mg vial with 2mL bacteriostatic water is working in milligrams - but the moment they draw into a U-100 insulin syringe, they're reading in units. That unit-to-volume translation is where errors happen.
ASCEND exists to be the single source of truth for that calculation. Enter your vial size, water volume, and target dose - the app returns the exact syringe marking to draw to, no conversion table needed. For blended vials (GHK-Cu + BPC-157 + TB-500, for example), it handles each peptide's ratio independently so the math stays correct regardless of stack complexity.
All syringe calculations are based on the U-100 insulin syringe standard: 1mL = 100 units. This is the industry-universal scale used in peptide research - a 10-unit mark equals 0.10mL regardless of the syringe brand.
Concentration is derived from the vial's labeled peptide mass divided by the volume of reconstitution solution added. Dose-to-volume conversion then divides the target dose by that concentration. For multi-peptide blends, each component's ratio is calculated independently against the total vial mass before applying the same pipeline - ensuring accuracy when peptides share a single vial at different weights.
The mathematical logic and dosing presets within ASCEND are derived from clinical trial data and peer-reviewed literature, including:
All clinical presets are cross-referenced with Phase 2 and Phase 3 trial data. While these presets represent the protocols used in clinical settings, ASCEND is designed solely for mathematical calculation and research organization.
WARNING: ASCEND IS A MATHEMATICAL TOOL FOR RESEARCH PURPOSES ONLY.
It is not a medical device and does not provide medical advice, dosing recommendations, or treatment plans. Calculations are provided as-is for informational and educational use. Always verify outputs independently and consult a qualified healthcare professional before beginning any research protocol. Peptide research compounds are not FDA-approved for human therapeutic use in most jurisdictions.
All calculations run locally on your device. ASCEND is built with vanilla JavaScript - there is no server-side computation, no data sent to external APIs for your inputs, and no tracking of what you calculate. Your vial sizes, doses, and protocol details never leave your browser.
Account data (saved protocols, preferences) is stored in Supabase with row-level security - only your account can read your records. You can use every calculator on this site without signing in.
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