A triple GIP/GLP-1/glucagon receptor agonist for weight management and metabolic health.
TL;DR — Retatrutide is a metabolic & weight peptide with a typical starting dose of 0.5 mg. For a 10 mg vial, add 2 mL bacteriostatic water to yield 5 mg/mL.
Add 2 mL of bacteriostatic water to a 10 mg vial, injecting slowly down the inside wall. Swirl gently; never shake. This yields a concentration of 5 mg/mL.
What is the recommended dose of Retatrutide?
A typical research dose is 0.5 mg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a Retatrutide vial?
A 10 mg vial reconstituted with 2 mL BAC water yields approximately 20 doses at 0.5 mg each.
Peptide Intelligence
What is the half-life of Retatrutide?
Retatrutide has a half-life of approximately 6 days, supporting once-weekly subcutaneous dosing. This extended half-life is achieved through fatty acid side-chain technology similar to other long-acting GLP-1 receptor agonists.
How does Retatrutide differ from Tirzepatide?
Retatrutide is a triple agonist targeting GIP, GLP-1, and glucagon receptors, while Tirzepatide is a dual GIP/GLP-1 agonist. The addition of glucagon receptor activity may drive greater energy expenditure and fat oxidation per unit dose.
What are proper storage conditions for Retatrutide?
Store reconstituted Retatrutide at 2–8°C and protect from light. Do not freeze. Lyophilized powder can typically be stored at room temperature for short periods; refrigeration is preferred for long-term stability.