⚖ Head-to-Head · Selank vs Amidated Form

Selank vs N-Acetyl Selank Amidate

Mechanism, half-life, dosing & research status compared side-by-side.

Selank
Cognitive & Anxiolytic
Not Approved
CognitiveAnxiolyticNootropicImmune
Selank is a synthetic analog of the immunomodulatory tetrapeptide tuftsin (Thr-Lys-Pro-Arg), extended with Pro-Gly-Pro for metabolic stability. Developed at the Institute of Molecular Genetics in Russia, it is approved a…
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N-Acetyl Selank Amidate
Cognitive & Neurological
Not Approved
CognitiveAnxiolyticNootropicIntranasalBDNF
N-Acetyl Selank Amidate is a doubly-modified form of Selank (a synthetic heptapeptide based on tuftsin) with N-acetylation at the N-terminus and amidation at the C-terminus. These modifications extend enzymatic stability…
Full N-Acetyl Selank Amidate profile →
Technical Specs Comparison
MetricSelankN-Acetyl Selank Amidate
Research Status Extensively Studied Research Use
Molecular Weight 751.9 Da ~900 Da (modified)
Half-Life ~2 min (plasma); CNS effects 24h+ ~6–8 hours (estimated; extended vs. standard Selank)
Peak Time ~30 min (intranasal) -
Typical Dose 250–750 µg intranasal 100–300 µg
Frequency Once or twice daily Once or twice daily
Route Intranasal (primary) / Subcutaneous Intranasal
Amino Acids 7 7
WADA Status Not Listed Not Listed
FDA Status Not Approved Not Approved
Stack Compatibility & Key Differences
Both are active research compounds. See individual pages for full protocol data.
PK Plotter
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Frequently Asked Questions
What is the difference between Selank and N-Acetyl Selank Amidate?
Selank: Selank is a synthetic analog of the immunomodulatory tetrapeptide tuftsin (Thr-Lys-Pro-Arg), extended with Pro-Gly-Pro for metabolic stability. Developed at the Institute of Molecular Genetics in Russia, it is approved a… N-Acetyl Selank Amidate: N-Acetyl Selank Amidate is a doubly-modified form of Selank (a synthetic heptapeptide based on tuftsin) with N-acetylation at the N-terminus and amidation at the C-terminus. These modifications extend enzymatic stability…
Can you stack Selank and N-Acetyl Selank Amidate?
Both are active research compounds. See individual pages for full protocol data.
Which has a longer half-life, Selank or N-Acetyl Selank Amidate?
Selank half-life: ~2 min (plasma); CNS effects 24h+. N-Acetyl Selank Amidate half-life: ~6–8 hours (estimated; extended vs. standard Selank).
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Verified Scientific Data
All specifications on this page are sourced from peer-reviewed literature and primary research. Half-life values, dosing ranges, and mechanism data are cross-referenced against published studies. Last audited 2026-06-15.
● Peer-reviewed sources ● Audit timestamp: 2026-06-15 ● Data version: ASCEND Wiki 2026
Data sourced from ASCEND Wiki · Selank profile · N-Acetyl Selank Amidate profile · All comparisons
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