⚖ Head-to-Head · GHRH vs GHRP

Sermorelin vs GHRP-2

Mechanism, half-life, dosing & research status compared side-by-side.

Sermorelin
Growth Hormone
Compounding Only
Growth HormoneAnti-agingRecoverySleep
Sermorelin is a synthetic analog of the first 29 amino acids of endogenous GHRH, retaining full biological activity at the GHRH receptor. It was FDA approved (Geref) for GH deficiency in children from 1997 until its volu…
Full Sermorelin profile →
GHRP-2
Growth Hormone
Not Approved (US)
Growth HormoneBody CompositionRecovery
GHRP-2 (Pralmorelin) is a synthetic hexapeptide growth hormone releasing peptide and one of the most potent first-generation GHRPs. It stimulates pituitary GH secretion via the ghrelin receptor (GHSR-1a) with greater pot…
Full GHRP-2 profile →
Technical Specs Comparison
MetricSermorelinGHRP-2
Research Status Extensively Studied Extensively Studied
Molecular Weight 3,357.9 Da 817.9 Da
Half-Life ~10–20 min ~30–60 min
Peak Time ~30–60 min ~30–45 min
Typical Dose 200–500 µg 100–300 µg
Frequency Once daily (bedtime) 1–3× daily
Route Subcutaneous Subcutaneous
Amino Acids 29 6
WADA Status Prohibited Prohibited
FDA Status Compounding Only Not Approved (US)
Stack Compatibility & Key Differences
Both are active research compounds. See individual pages for full protocol data.
Frequently Asked Questions
What is the difference between Sermorelin and GHRP-2?
Sermorelin: Sermorelin is a synthetic analog of the first 29 amino acids of endogenous GHRH, retaining full biological activity at the GHRH receptor. It was FDA approved (Geref) for GH deficiency in children from 1997 until its volu… GHRP-2: GHRP-2 (Pralmorelin) is a synthetic hexapeptide growth hormone releasing peptide and one of the most potent first-generation GHRPs. It stimulates pituitary GH secretion via the ghrelin receptor (GHSR-1a) with greater pot…
Can you stack Sermorelin and GHRP-2?
Both are active research compounds. See individual pages for full protocol data.
Which has a longer half-life, Sermorelin or GHRP-2?
Sermorelin half-life: ~10–20 min. GHRP-2 half-life: ~30–60 min.
Verified Scientific Data
All specifications on this page are sourced from peer-reviewed literature and primary research. Half-life values, dosing ranges, and mechanism data are cross-referenced against published studies. Last audited 2026-06-15.
Peer-reviewed sources Audit timestamp: 2026-06-15 Data version: ASCEND Wiki 2026
Data sourced from ASCEND Wiki · Sermorelin profile · GHRP-2 profile · All comparisons
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